The four horseman of the mental health apocalypse
Discover the four hidden biochemical forces driving mental health and learn how to target them effectively in clinical practice.
Improve client outcomes: Home study course
The Four Horsemen of the Mental Health Apocalypse is an over 3 hour, online, on-demand video course designed specifically for nutritional therapists, dieticians, and other health practitioners. Led by renowned nutrition expert Patrick Holford, this training explores four powerful biochemical drivers of brain health - brain fats, methylation, glycation, and oxidation - and how they interact to influence cognition, mood, and long-term mental wellbeing.
Across four in-depth units, you’ll gain a clear understanding of the evidence behind each “horseman,” including how omega-3s, B vitamins, blood sugar balance, and antioxidant status shape neurological function. Patrick breaks down the mechanisms, relevant nutrient interactions, medication impacts, and key markers to watch for in clinical practice. Each module includes practical guidance on food sources, supplementation strategies, testing approaches, and how these factors connect to real-world client presentations.
This course is ideal for practitioners seeking to deepen their confidence in addressing mental health from a nutritional and functional perspective. It can be viewed at your own pace and revisited whenever needed, making it a valuable resource you can return to as you integrate these insights into client support plans.
About Patrick:
Patrick Holford BSc, DipION, FBANT, NTCRP
- Patrick is a retired visiting professor, specialising in nutrition and mental health, author of 46 books and is in the Orthomolecular Medicine Hall of Fame
- ION Founder Patron - In 1984 Patrick founded the Institute for Optimum Nutrition
- Food for the Brain charity Founder and Chair of the Scientific Advisory Board

